Asterand Isolates New Approach to Arthritis Research



    Asterand (LSE:ATD), the human tissue research company, announced
    today that it is making available new research materials to be used in
    the investigation of rheumatoid arthritis, osteoarthritis, cancer and
    other diseases.

    The company is offering researchers cells that have been isolated
    from various parts of the body, including synovium from the joints of
    patients suffering from rheumatoid arthritis and cartilage from
    patients with osteoarthritis. "Cells are available from cultures
    preserved after minimal time in the laboratory," says Dr. Vici Blanc,
    Director of Product Development. "This approach is important because
    cells can change over time under laboratory conditions and scientists
    need them to remain closely resembling those which are in the body."

    "Minimal and zero passage cells provide researchers with excellent
    systems for analyzing drug action in living human cells and for
    understanding the molecular progression of diseases."

    Asterand produces these cells in its laboratories by propagating
    them for limited periods of time and then cryo-preserving them after a
    minimal number of passages. The full range of cells available includes
    chondrocytes, synovial fibroblasts, epithelial cells and carcinoma
    associated fibroblasts.

    "Much of this material is very hard to obtain. We may be the only
    company in the world that is able to offer this research approach,"
    adds Dr. Blanc. "We are uniquely positioned to obtain these samples
    because we operate a worldwide network of collection sites where
    patients have the opportunity to donate fully de-identified samples
    for research."

    Researchers anywhere in the world will be able to order synovial
    cells for arthritis research through Asterand's online catalogue at
    http://solutions.asterand.com/ or via Asterand's laboratories in
    Detroit, Michigan and Royston, UK.

    "We are able to collect samples for cell culture and
    cryopreservation on a custom basis," says Dr. Blanc. "So if
    researchers have special needs for isolated cells which are not
    immediately available, Asterand may be able to help them."

    Asterand plc is a UK public company that supports human drug
    discovery and translational medicine through the provision of high
    quality, well characterized human biomaterials and preclinical
    research services. The company maintains banks of samples including
    breast, lung, prostate, colon and other cancers, diabetes,
    cardiovascular and central nervous system diseases. Asterand also
    performs contract research services on behalf of its clients. The
    company's mission is to provide the highest quality human biological
    material and services to researchers developing better diagnostics and
    therapeutics.