CORRECTING and REPLACING Australian and New Zealand College of Anaesthetists and Madrid Centro Society for Anesthesia Publish Recommendations for Monitoring During Anaesthesia



    Please replace the release dated August 24, 2006 with
    the following corrected version due to multiple revisions.

    The corrected release reads:

    AUSTRALIAN AND NEW ZEALAND COLLEGE OF ANAESTHETISTS AND MADRID
    CENTRO SOCIETY FOR ANESTHESIA PUBLISH RECOMMENDATIONS FOR MONITORING
    DURING ANAESTHESIA

    Aspect Medical Systems (NASDAQ: ASPM) today announced that the
    Australian and New Zealand College of Anaesthetists (ANZCA) and the
    Madrid Centro Society for Anesthesia (MCSA) have each published
    recommendations for monitoring level of consciousness during
    anaesthesia. These recommendations were written to guide ANZCA and
    MCSA members in recognizing the problem of unintended awareness and
    adopt a consensus on how to reduce the incidence of inadvertent
    surgical wake-ups. Unintended awareness occurs when patients do not
    receive enough anaesthesia, leaving them at risk for becoming aware of
    what is happening and remembering this experience after the surgery is
    over.
    "The ANZCA and MCSA recommendations are consistent with the
    clinical guidance provided by other medical societies in the United
    States and Europe and reflect an increasing global recognition of the
    need to address awareness as a patient safety concern," said Nassib
    Chamoun, president and CEO of Aspect. "We believe this is an important
    step toward improving patient safety and reducing the risk of
    awareness. BIS is the only brain monitoring technology or clinical
    intervention that has been shown in large scale, prospective clinical
    research to reduce the incidence of awareness."

    Australian and New Zealand College of Anaesthestists Guidance to
    Clinicians

    The ANZCA has stated that, when clinically indicated, equipment to
    monitor the anaesthetic effect on the brain should be available for
    use on patients at high risk of awareness during general anaesthesia.
    To view the ANZCA recommendations, visit
    http://www.medeserv.com.au/anzca/pdfdocs/PS18-2006.pdf.

    Madrid Centro Society for Anesthesia Guidance to Clinicians

    The MCSA issued a consensus statement recommending that depth of
    consciousness monitors should be available for patients at high risk
    for awareness during general anaesthesia and supports education on how
    to best use the monitors to reduce the incidence of intraoperative
    awareness. The Society defines preventative measures that apply to the
    clinician, the equipment, the medical staff, and the patient,
    identifying a list of high-risk patient characteristics. To view the
    complete statement of the MCSA working group regarding unintended
    awareness, visit
    http://www.sarmadrid.org/pdf/despertar_intraoperatorio_maqueta1.pdf.
    The ANZCA and MCSA recommendations follow similar statements made
    by the American Society of Anesthesiologists
    (www.asahq.org/publicationsAndServices/AwareAdvisoryFinalOct05.pdf),
    JCAHO
    (www.jointcommission.org/SentinelEvents/SentinelEventAlert/sea_32.htm)
    the American Association of Nurse Anesthetists
    (http://www.aana.com/Resources.aspx?ucNavMenu_TSMenuTargetID=51&
    ucNavMenu_TSMenuTargetType=4&ucNavMenu_TSMenuID=6&id=1747), and the
    Royal College of Anaesthetists and the Association of Anaesthetists of
    Great Britain and Ireland
    http://www.aagbi.org/release_lossofconsciousness.html.

    About BIS Monitoring

    Using a sensor placed on the patient's forehead, BIS monitoring
    translates information from the electroencephalogram (EEG) into a
    single number that represents each patient's level of consciousness.
    This number - the BIS value - ranges from 100 (indicating an awake
    patient) to zero (indicating the absence of brain activity). Using the
    BIS value to guide administration of anesthetic medication, in
    conjunction with other vital signs, allows clinicians to make
    better-informed decisions to achieve optimal anesthesia.

    About Aspect Medical Systems, Inc.

    Aspect Medical Systems, Inc. (NASDAQ: ASPM) is a global market
    leader in brain monitoring technology. To date, the Company's
    Bispectral Index (BIS) technology has been used to assess more than
    16.3 million patients and has been the subject of approximately 2,370
    published articles and abstracts. BIS technology is installed in
    approximately 68 percent of hospitals listed in the July 2006 U.S.
    News and World Report ranking of America's Best Hospitals and in
    approximately 49 percent of all domestic operating rooms. In the last
    twelve months BIS technology was used in approximately 15 percent of
    all U.S. surgical procedures requiring general anesthesia or deep
    sedation. BIS technology is available in more than 160 countries.
    Aspect Medical Systems has OEM agreements with seven leading
    manufacturers of patient monitoring systems. The company is also
    investigating how other methods of analyzing brain waves may aid in
    the diagnosis and management of neurological diseases, including
    depression and Alzheimer's disease. For more information, visit
    Aspect's Web site at http://www.aspectmedical.com.

    Safe Harbor Statement

    Certain statements in this release are forward-looking and may
    involve risks and uncertainties, including statements regarding the
    role of brain function monitoring and its effect on the safety and
    quality of anesthesia care. There are a number of important factors
    that could cause actual results to differ materially from those
    indicated by these forward-looking statements. For example, the
    Company may not achieve widespread market acceptance of its BIS
    monitoring technology among anesthesiologists. The Company also faces
    other barriers to market penetration and acceptance. The Company may
    not be able to compete with new products or alternative techniques
    that may be developed by others, including third-party anesthesia
    monitoring products approved by the FDA, and also faces competitive
    and regulatory risks relating to its ability to successfully develop
    and introduce enhancements and new products, including products to aid
    in the treatment of neurological disorder. Cases of awareness with
    recall during monitoring with the BIS system and significant product
    liability claims are among the factors that could limit market
    acceptance. There are additional factors that could cause the
    Company's actual results to vary from its forward-looking statements,
    including without limitation those set forth under the heading "Risk
    Factors" in the Company's Annual Report on Form 10-K for the fiscal
    year ended December 31, 2005 and the Company's Quarterly Report on
    Form 10-Q for the fiscal quarter ended July 1, 2006, each as filed
    with the Securities and Exchange Commission. In addition, any
    forward-looking statements represent the Company's views only as of
    the date of this press release and should not be relied upon as
    representing the Company's views as of any subsequent date. While the
    Company may elect to update forward-looking statements in the future,
    it specifically disclaims any obligation to do so, even if its
    expectations change. Therefore, you should not rely on these
    forward-looking statements as representing the Company's views as of
    any date subsequent to the date of this press release.

    Aspect, Bispectral Index and BIS are registered trademarks of
    Aspect Medical Systems, Inc. All other trademarks, service marks and
    company names are the property of their respective owners.