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OMRIX Biopharmaceuticals Receives FDA Approval for Second Generation Fibrin Sealant, Evicel(TM), For Use in Liver Surgery; Submits Evicel Phase III Study to FDA for Expanded Indication in Peripheral Vascular Surgery



    - Company Advances Expanded General Hemostasis Surgery Indication
    and Leadership Position in Surgical Hemostasis Market -

    OMRIX Biopharmaceuticals, Inc. ("OMRIX" or "The Company") (NASDAQ:
    OMRI), a commercial-stage biopharmaceutical company that develops and
    markets biosurgical and passive immunotherapy products, announced
    today that it has been granted marketing clearance from the U.S. Food
    and Drug Administration (FDA) for its second generation fibrin
    sealant, Evicel(TM), to control bleeding (hemostasis) during liver
    surgery. Evicel differs from OMRIX's first generation fibrin sealant,
    Crosseal(R), in that Evicel does not contain a stabilizer, and
    therefore will not have the neurosurgical contraindication required of
    Crosseal.
    The Company also announced that it submitted a Prior Approval
    Supplement (PAS) to the FDA containing the results of a prospective,
    randomized multi-center Phase III controlled study comparing the
    hemostatic efficacy of Evicel to standard-of-care in peripheral
    vascular surgery in 150 patients. The first subject was randomized on
    June 9, 2005 and the last subject completed the study on March 29,
    2006. OMRIX submitted this PAS in order to expand the indication of
    Evicel to include vascular surgery.
    "Together with our distributor, ETHICON, Inc., we are re-defining
    the hemostasis market," stated Robert Taub, President and Chief
    Executive Officer of OMRIX Biopharmaceuticals, Inc. "Uncontrolled
    surgical bleeding is a severe clinical issue. We are poised to provide
    today's market with the safest and most technically superior products
    that address the need for effective and quick hemostasis."
    Mr. Taub continued, "An indication for general hemostasis requires
    the completion of at least three pivotal clinical studies, of which we
    have now completed two -- liver and peripheral vascular surgery. A 150
    patient study in kidney surgery is currently underway. The achievement
    of today's strategically important milestones provides a foundation on
    which to expand the commercialization potential of our hemostasis
    franchise, and brings us one step closer to a general hemostasis label
    of Evicel, our liquid fibrin sealant. We look forward to announcing
    additional validating events for Evicel and our other biosurgical
    products: Thrombin and Biological Hemostatic Dressing, or BHD."

    Evicel's Competitive Advantages

    Evicel is unique in its ease of use, immediate availability to the
    surgeon and in its bovine-free formulation. It provides for important
    hemostasis support when conventional surgical techniques (i.e.,
    suture, ligature, and cautery) prove to be inefficient, ineffective or
    impractical. When compared to the already successful Crosseal, Evicel
    does not require the addition of the stabilizing agent Tranaxemic
    Acid.

    About OMRIX Biopharmaceuticals, Inc.

    OMRIX, a commercial-stage biopharmaceutical company, develops and
    markets innovative biosurgical and passive immunotherapy products,
    utilizing its proprietary protein purification technology and
    manufacturing know-how. As part of its business strategy, OMRIX
    commercializes certain of its biosurgical products through
    collaborations with companies whose marketing and sales expertise are
    a complement to OMRIX's own areas of specialty. OMRIX's novel and
    easy-to-use biological-device convergence products address unmet
    medical needs. For more information, please visit: www.omrix.com.

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