Rosetta Biosoftware Announces the Availability of the Rosetta Elucidator Protein Expression Data Management and Analysis System Version 2.0



    New Version to be Showcased at Workshop at 54th Annual ASMS Conference
    on Mass Spectrometry

    Rosetta Biosoftware today announced the availability of version
    2.0 of the Rosetta Elucidator(R) protein expression data analysis
    system, with capabilities to support data from additional mass
    spectrometry instrument types and integrate with additional search
    engines. The Elucidator system version 2.0 is a comprehensive
    informatics solution for protein biomarker discovery. The latest
    version supports data from Thermo Finnigan(TM) LTQ FT and LTQ
    Orbitrap(TM), Waters(R) Q-TOF Premier(TM), and Applied Biosystems
    QSTAR(R) instruments and integrates with the Mascot, Sequest, and
    Sage-N Research's Sorcerer search engines.
    "To develop the latest version of the Elucidator system, we
    incorporated important feedback from users," said Yelena Shevelenko,
    vice president and general manager of Rosetta Biosoftware. "In
    addition to adding support for more instruments and search engines, we
    have made key enhancements to visualization and productivity tools,
    such as adding the 2D Image Viewer for quickly evaluating LC/MS data,
    and adding a tool to rapidly generate a list of
    differentially-expressed proteins. These enhancements increase
    productivity and accommodate diverse users."
    "The Elucidator system has improved our research productivity
    because we can do analyses that could not easily be done before,"
    states Michael G. Katze, Ph.D., Professor of Microbiology, University
    of Washington, and Associate Director of the Washington National
    Primate Research Center. "The powerful combination of the Resolver
    system for genomics and the Elucidator system for proteomics has
    enabled my laboratory to begin integrating mRNA and protein data at a
    global level for the first time. Because of the tremendous
    capabilities of Rosetta Biosoftware's informatics tools, we are
    beginning to make great strides towards our understanding of deadly
    viral diseases such as pandemic influenza, hepatitis C virus, and
    AIDS."
    Further information about the Elucidator system version 2.0 will
    be presented at the American Society for Mass Spectrometry (ASMS)
    annual meeting in Seattle, WA, May 28-June 1. To learn more about this
    conference, please visit http://www.asms.org/.

    About the Elucidator System

    The Elucidator system's advanced data management capabilities
    allow users to effectively organize, search for, and retrieve raw and
    processed protein expression data. The application serves as a core
    integrator for proteomics research by working directly with select
    instrument APIs, sample annotation systems, and common protein ID
    search engines. In addition, it provides a suite of advanced
    statistical analysis and visualization tools for data mining and
    discovery of potential protein biomarkers and proteins that are
    differentially expressed among different phenotypes or drug
    treatments. The Elucidator system combines these data management and
    analysis capabilities with the flexibility of a highly customizable
    environment: users can incorporate organization-specific workflows
    into customized visual scripts that leverage Elucidator system
    statistical tools and customer-proprietary algorithms, as well as
    those available in the public domain. The Rosetta Elucidator product
    line is available in flexible configurations, designed to meet the
    needs of both large and small organizations.

    About Rosetta Biosoftware

    Rosetta Biosoftware is a leading provider of informatics solutions
    for life science research. Its comprehensive software solutions,
    including the Rosetta Resolver and Rosetta Elucidator systems, empower
    life scientists with advanced, scalable, and easy-to-use analysis
    platforms that accelerate discovery research. Rosetta Biosoftware is a
    business unit of Rosetta Inpharmatics LLC, a wholly owned subsidiary
    of Merck & Co., Inc. (NYSE:MRK). More information about Rosetta
    Biosoftware is available at www.rosettabio.com.

    Forward-Looking Statements

    This press release contains "forward-looking statements" as that
    term is defined in the Private Securities Litigation Reform Act of
    1995. These statements involve risks and uncertainties, which may
    cause results to differ materially from those set forth in the
    statements. The forward-looking statements may include statements
    regarding product development, product potential, or financial
    performance. No forward-looking statement can be guaranteed, and
    actual results may differ materially from those projected. Neither
    Rosetta Inpharmatics nor Merck & Co., Inc. undertakes any obligation
    to publicly update any forward-looking statement, whether as a result
    of new information, future events, or otherwise. Forward-looking
    statements in this press release should be evaluated together with the
    many uncertainties that affect the business of Merck & Co., Inc.
    including, among others, the extent to which Rosetta Inpharmatics'
    technology platform can be used in drug discovery programs,
    uncertainty of market acceptance of Rosetta Inpharmatics'
    technologies, ability to compete against existing technologies, and
    those mentioned in the cautionary statements in Item 1 of Merck's Form
    10-K for the year ended Dec. 31, 2005, and in its periodic reports on
    Form 10-Q and Form 8-K (if any) which are incorporated by reference.

    Rosetta Resolver and Elucidator are U.S. registered trademarks of
    Rosetta Inpharmatics LLC.