Response Genetics, Inc. Launches ResponseDX(TM) Tests to Select Institutions



    Response Genetics, Inc. (NASDAQ: RGDX) announced today that its
    ResponseDX: Lung(TM) and ResponseDX: Colon(TM) tests are now available
    to select medical institutions and practice groups through its
    CLIA-registered laboratory. ResponseDX: Lung(TM) and ResponseDX:
    Colon(TM) are PCR-based tests that help guide therapeutic treatment
    decisions in patients with non-small cell lung cancer (NSCLC) and
    colorectal cancer (CRC). The tests are in their initial launch phase
    and are available only to pre-qualified institutions at this time.

    "ResponseDX: Lung(TM) and ResponseDX: Colon(TM) tests offer
    clinicians--and ultimately patients--a comprehensive view of the
    genetic factors that relate to a patient´s cancer therapies," said
    Kathy Danenberg, CEO and President of Response Genetics, Inc. "In this
    initial launch, we´ll continue to gather information from our
    participating clinical partners to further develop and expand our
    products and services."

    During this initial launch, Response Genetics, Inc. will gather
    additional data about the utility of these genetic tests, including
    excision cross-complementing repair factor 1 (ERCC1) gene expression,
    in the treatment of NSCLC and CRC; clinical practice activities such
    as sample acquisition, logistics, patient and physician communication;
    and the use of the test in normal clinical practice related to NSCLC
    and CRC. Response Genetics, Inc. also offers several genetic tests, in
    addition to ERCC1, that can use the same formalin-fixed
    paraffin-embedded (FFPE) tumor tissue sample, which eliminates the
    need for additional tumor samples.

    The complete genetic tests offered for patients with NSCLC or CRC
    include:

    ERCC1 Gene Expression

    Available in ResponseDX: Lung(TM) and ResponseDX: Colon(TM): This
    test measures ERCC1 gene expression, a molecular marker to identify
    NSCLC and CRC patients who may and may not benefit from platinum-based
    therapy.

    KRAS Mutations

    Available in ResponseDX: Lung(TM) and ResponseDX: Colon(TM): This
    test determines whether or not the K-ras gene (KRAS) contains
    mutations. A mutated KRAS is a very strong predictor of non-response
    and no benefit from the epidermal growth factor receptor (EGFR)
    inhibitors erlotinib and gefitinib.

    EGFR Amplification

    Available in ResponseDX: Lung(TM): This test measures the number
    of copies (gene amplification) of EGFR. A high number of gene copies
    has been shown to correlate with increased response of NSCLC to the
    EGFR inhibitors erlotinib and gefitinib.

    RRM1 Gene Expression

    Available in ResponseDX: Lung(TM): This test measures RRM1 gene
    expression, a molecular marker to identify NSCLC patients who may and
    may not benefit from chemotherapy regimens that include gemcitabine.

    TS Gene Expression

    Available in ResponseDX: Colon(TM): This test determines the level
    of gene expression of thymidylate synthase (TS) in tumor tissue. TS
    expression is a predictor of response to fluoropyrimidine-based
    chemotherapy.

    Response Genetics, Inc. Adds Vice President, Sales and Marketing
    Position

    In addition to the initial ResponseDX: Lung(TM) and ResponseDX:
    Colon(TM) launch, Response Genetics, Inc. announces the appointment of
    Chris Emery as Vice President, Sales and Marketing. Chris will be
    responsible for overall marketing strategy and sales of the company´s
    suite of genetic tests to the healthcare community. Chris has more
    than 10 years experience in the diagnostic and therapeutic industries,
    and most recently he was the Director of Marketing for Insight
    Imaging, a provider of diagnostic imaging services. Prior to Insight
    Imaging, Chris was a National Sales Manager at US LABS, a cancer
    diagnostic division of LabCorp.

    Chris graduated from Pepperdine University with an Executive MBA
    in 2006, and from the University of California, San Diego, with a BA
    in Communication Studies in 1994.

    Response Genetics, Inc. Annual Strategic Update

    Response Genetics, Inc. will announce full year financial results
    and host an annual strategic update conference call on Wednesday,
    March 26. As the date approaches the Company will release the
    conference call time, dial-in numbers, and webcast information.

    About Response Genetics, Inc.

    Response Genetics, Inc. ("RGI") (NASDAQ: RGDX) is engaged in the
    research and development of pharmacogenomic cancer diagnostic tests
    based on its proprietary and patented technologies. RGI´s technologies
    enable extraction and analysis of genetic information from genes
    derived from tumor samples stored as formalin-fixed and paraffin
    embedded specimens. RGI currently generates revenue primarily from the
    sales of its proprietary analytical pharmacogenomic testing services
    of clinical trial specimens to the pharmaceutical industry. The
    company was founded in 1999 and its principal headquarters are located
    in Los Angeles, California. For more information, please visit
    www.responsegenetics.com.

    Forward Looking Statement Notice

    Except for the historical information contained herein, this press
    release and the statements of representatives of Response Genetics,
    Inc. (the "Company") related thereto contain or may contain, among
    other things, certain forward-looking statements, within the meaning
    of the Private Securities Litigation Reform Act of 1995. Such
    forward-looking statements involve significant risks and
    uncertainties. Such statements may include, without limitation,
    statements with respect to the Company´s plans, objectives,
    projections, expectations and intentions, such as the ability of the
    Company to analyze cancer samples, the potential for using the results
    of this research to develop diagnostic tests for cancer, the
    usefulness of genetic information to tailor treatment to patients, the
    ability of the Company to make its ResponseDx:Lung(TM) and
    ResponseDX:Colon(TM) tests, including its ERCC-1 molecular diagnostic
    test available in the first quarter of 2008, or at all, and other
    statements identified by words such as "projects", "may", "could",
    "would", "should", "believes", "expects", "anticipates", "estimates",
    "intends", "plans" or similar expressions.

    These statements are based upon the current beliefs and
    expectations of the Company´s management and are subject to
    significant risks and uncertainties, including those detailed in the
    Company´s filings with the Securities and Exchange Commission. Actual
    results, including, without limitation, actual sales results, if any,
    or the application of funds, may differ from those set forth in the
    forward-looking statements. These forward- looking statements involve
    certain risks and uncertainties that are subject to change based on
    various factors (many of which are beyond the Company´s control). The
    Company undertakes no obligation to publicly update forward-looking
    statements, whether because of new information, future events or
    otherwise, except as required by law.