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Response Genetics, Inc. to Perform the MAGE-A3 Screening Assay for the Current GlaxoSmithKline Phase III Novel MAGE-A3 Cancer Immunotherapeutic in Non-Small Cell Lung Cancer



    Response Genetics, Inc. (NASDAQ: RGDX) today announced that it has
    begun performing the MAGE-A3 gene expression screening assay for
    GlaxoSmithKline´s (GSK) Phase III clinical trial of the
    investigational MAGE-A3 Antigen-Specific Cancer Immunotherapeutic
    (ASCI) as adjuvant therapy in MAGE-A3 positive patients with stage IB,
    II or IIIA Non-Small Cell Lung Cancer (NSCLC). These assays will be
    performed in formalin-fixed paraffin-embedded tissue.

    "We are pleased to be working with GlaxoSmithKline in support of
    this important clinical trial," said Kathleen Danenberg, President and
    CEO of Response Genetics. "This would be the largest clinical trial
    ever conducted in lung cancer treatment and, with approximately 35 to
    50 percent of early NSCLC expressing the MAGE-A3 tumor-specific
    antigen, we are excited to be involved and to be providing our
    biomarker analysis."

    GSK has begun recruiting for a Phase III trial evaluating MAGE-A3
    ASCI as adjuvant therapy in MAGE-A3 positive patients with NSCLC. With
    a target of about 2,270 patients, the randomized, double-blind, and
    placebo-controlled MAGRIT trial will enroll patients with stage IB, II
    or IIIA resected NSCLC. This would be the largest clinical trial ever
    conducted in lung cancer treatment. All patients participating in the
    trial have cancers expressing a tumor-specific antigen, MAGE-A3, which
    is present in approximately 35 to 50 percent of early NSCLC. The
    primary endpoint of the trial is disease-free survival.

    About Response Genetics, Inc.

    Response Genetics, Inc. ("RGI") (NASDAQ: RGDX) is engaged in the
    research and development of pharmacogenomic cancer diagnostic tests
    based on its proprietary and patented technologies. RGI´s technologies
    enable extraction and analysis of genetic information from genes
    derived from tumor samples stored as formalin-fixed and paraffin
    embedded specimens. RGI currently generates revenue primarily from the
    sales of its proprietary analytical pharmacogenomic testing services
    of clinical trial specimens to the pharmaceutical industry. The
    company was founded in 1999 and its principal headquarters are located
    in Los Angeles, California. For more information, please visit
    www.responsegenetics.com.

    Forward Looking Statement Notice

    Except for the historical information contained herein, this press
    release and the statements of representatives of Response Genetics,
    Inc. (the "Company") related thereto contain or may contain, among
    other things, certain forward-looking statements, within the meaning
    of the Private Securities Litigation Reform Act of 1995. Such
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    statements with respect to the Company´s plans, objectives,
    projections, expectations and intentions, such as the ability of the
    Company to analyze cancer samples, the potential for using the results
    of this research to develop diagnostic tests for cancer, the
    usefulness of genetic information to tailor treatment to patients, and
    other statements identified by words such as "projects," "may,"
    "could," "would," "should," "believes," "expects," "anticipates,"
    "estimates," "intends," "plans" or similar expressions. These
    statements are based upon the current beliefs and expectations of the
    Company´s management and are subject to significant risks and
    uncertainties, including those detailed in the Company´s filings with
    the Securities and Exchange Commission. Actual results, including,
    without limitation, actual sales results, if any, or the application
    of funds, may differ from those set forth in the forward-looking
    statements. These forward- looking statements involve certain risks
    and uncertainties that are subject to change based on various factors
    (many of which are beyond the Company´s control). The Company
    undertakes no obligation to publicly update forward- looking
    statements, whether because of new information, future events or
    otherwise, except as required by law.