Spinal Elements(TM) Announces Successful Completion of Landmark Spine Surgery



    Spinal Elements announced today that the first implantation of
    their highly-anticipated Zyre Facet Implant System in December 2007
    was a success. It is the first arthroplasty system developed
    specifically to address facet joint pain.

    Pioneer spine surgeon Rudolf Bertagnoli, M.D. performed the
    minimally-invasive, tissue-sparing procedure, which directly addresses
    the small facet joints present in every level of the spine. Top
    surgeons, Carl Lauryssen, M.D., of Tower Orthopedics in Beverly Hills,
    CA and Scott Kitchel, M.D., of Orthopedic Spine Associates in Eugene,
    Oregon, assisted in the procedure. It is the first of a set of
    surgeries being performed in Germany to evaluate the Zyre system
    performance.

    "This procedure represents a breakthrough in the treatment of
    chronic back pain," said Dr. Bertagnoli. "The technology provides a
    large population of patients living with chronic facet pain with an
    alternative to fusion or reliance on perpetual conservative treatments
    such as injections and manipulation."

    More than 50 percent of patients with chronic back pain exhibit
    some or most of that pain in the facet joints. A recently approved
    procedure called Total Disc Replacement (TDR) addresses degenerative
    disc disease (DDD), but fails to treat degenerative facet joints,
    which usually contribute to back pain in patients with DDD. Recent
    studies of patients who underwent TDR surgery indicate that over 50
    percent of patients have progression of facet joint disease two years
    following the TDR procedure. Additionally, symptomatic facet joints
    are the leading contraindication for TDR present in 91 percent of
    patients requesting TDR but later undergoing other spinal procedures.

    Currently, DePuy Spine, Inc., a unit of Johnson and Johnson,
    Synthes Inc., and Medtronic Sofamor Danek, Inc. have FDA-approved TDR
    products, but few companies have taken the next step into facet joint
    arthroplasty. Spinal Elements(TM) has distinguished itself by
    providing a procedure to augment the facet joints instead of removing
    them. Spinal Elements believes the market potential for its Zyre(TM)
    Facet Implant System may approach one billion dollars annually.

    "We are very encouraged by this first procedure and believe there
    is a vast opportunity for the application of this technology,"
    commented Jason Blain, Chief Technology Officer for the Spinal
    Elements. "We believe the Zyre system will offer a host of patients
    surgical options in the future that simply are not available today."

    About Spinal Elements, Inc.

    Spinal Elements Inc., headquartered in Carlsbad, California, is a
    spine technology company with unique spinal implant technologies that
    are marketed throughout the US. Spinal Elements is focused on
    developing innovative fusion and spine motion preservation
    technologies. Spinal Elements currently markets a full line of
    commercially successful spinal implants. The worldwide spine market is
    valued at over $5 billion and growing at a rate greater than 20
    percent annually. Chronic back pain is the largest cause for missed
    work and among the most frequent reason patients visit physicians.
    Zyre is an investigational device and is not currently available in
    the United States.

    Additional information is available on the company website at
    www.spinalelements.com.

    Further inquires may be sent to zyre@spinalelements.com.