IntegraGen Becomes First Certified French Service Provider for Illumina GoldenGate and Infinium Genotyping



    Concurrent with the annual European Human Genetics Conference in
    Nice, France, Illumina, Inc. (NASDAQ:ILMN) announced today that
    IntegraGen SA, a personalized healthcare company focused on the
    development and commercialization of molecular diagnostic tests for
    complex diseases and provider of genetic services, has received
    Illumina Certified Service Provider (CSPro(TM)) certification for
    GoldenGate(R) and Infinium(R) genotyping technologies.

    Illumina, a San Diego-based company, is a leading developer,
    manufacturer, and marketer of next-generation life science tools and
    integrated systems for the analysis of genetic variation and
    biological function. The GoldenGate assay is Illumina's first
    array-based platform that combines high-sample throughput, high
    multiplexing, and single-site CpG resolution for DNA methylation
    profiling. The Infinium Whole-Genome Genotyping BeadArray(TM) solution
    offers single or multi-sample BeadChip formats and high-density
    architecture with the flexibility to add additional custom SNP Assays.

    "IntegraGen is a company dedicated to offering high-quality
    services to other research institutes, either private or academic, and
    is the first laboratory in France to achieve CSPro certification for
    GoldenGate and Infinium Genotyping," said Karen Possemato, Illumina's
    Director of Corporate Marketing. "By becoming a member of CSPro, they
    have further demonstrated their commitment to the life science
    community, providing delivery of the highest-quality data available
    for genetic analysis applications."

    Emmanuel Martin, IntegraGen's Director of Services and Arrays,
    said: "IntegraGen is proud of its ability to leverage core
    competencies and provide genetic services to the research community.
    Receiving Illumina CSPro certification is an endorsement of both
    Illumina and IntegraGen's commitment to quality, and provides our
    customers with even greater confidence in our ability meet their
    needs."

    As a customer of IntegraGen, Jessica Zucman-Rossi, M.D., Ph.D.,
    has been using Illumina technology in a pilot study for loss of
    heterozygosity (LOH) analysis in liver tumors at the Human
    Polymorphism Study Center (CEPH) in Paris. "We also chose Illumina
    technology to test for promoter methylation in liver tumors because
    there were a large number of genes available for testing with this
    system, and the ability to quantify methylation levels is a real
    advantage. My team was able to analyze a large number of samples in
    each experiment, and the time taken to generate results was short,
    generating a large amount of data." She added, "The results we
    attained were excellent, achieving methylation profiling of 96 tumor
    samples on more than 1,500 CpG. The data are robust, and we are
    currently preparing a second series of samples."

    About Illumina CSPro

    Illumina CSPro is a collaborative service provider partnership
    dedicated to ensuring the delivery of the highest-quality data
    available for genetic analysis applications. Illumina CSPros undergo a
    rigorous two-phase certification process that includes minimum data
    generation, data certification and on-site audit of the facility and
    processes. For more information about the CSPro program, please visit
    www.illumina.com/cspro.

    About IntegraGen

    IntegraGen is a pioneer in the field of predictive healthcare. The
    company uses its unique genomic analysis expertise to identify genes
    associated with complex diseases and commercializes molecular
    diagnostic tests to enable individualized diagnosis, prevention and
    treatment.

    IntegraGen's proprietary gene mapping technology GenomeHIP
    provides fast, reliable, and cost-effective discovery of genetic loci.
    Paired with strong biostatistics, bioinformatics and fine mapping
    genotyping capabilities, IntegraGen has successfully identified and
    patented genes associated with early and late onset diseases. Efforts
    are currently focused on Type-2 Diabetes, Obesity, Autism and Bi-Polar
    Disorder. Clinical trials for the company's first genetic test for
    autism, based on internally identified genes, were carried out in Q1
    2007.

    Founded in July 2000, IntegraGen has 34 employees and is based in
    the French Genopole of Evry, near Paris, France, in Bonn, Germany and
    in New York, USA. More information can be found at www.integragen.com.

    About Illumina

    Illumina is a leading developer, manufacturer and marketer of
    next-generation life science tools and integrated systems for the
    large scale analysis of genetic variation and biological function.
    Using our proprietary technologies, we provide a comprehensive line of
    products and services that currently serve the sequencing, genotyping,
    and gene expression markets, and we expect to enter the market for
    molecular diagnostics. Our customers include leading genomic research
    centers, pharmaceutical companies, academic institutions, clinical
    research organizations and biotechnology companies. Our tools provide
    researchers around the world with the performance, throughput, cost
    effectiveness and flexibility necessary to perform the billions of
    genetic tests needed to extract valuable medical information from
    advances in genomics and proteomics. We believe this information will
    enable researchers to correlate genetic variation and biological
    function, which will enhance drug discovery and clinical research,
    allow diseases to be detected earlier and permit better choices of
    drugs for individual patients.

    "Safe Harbor" Statement under the Private Securities Litigation
    Reform Act of 1995: this release may contain forward-looking
    statements that involve risks and uncertainties. Among the important
    factors that could cause actual results to differ materially from
    those in any forward-looking statements are the costs and outcome of
    Illumina's litigation with Affymetrix and our ability (i) to integrate
    effectively our recent acquisition of Solexa, Inc., (ii) to develop
    and commercialize further our BeadArray(TM), VeraCode(TM) and
    Solexa(R) technologies and to deploy new gene expression and
    genotyping products and applications for our technology platforms,
    (iii) to manufacture robust micro arrays and Oligator(R)
    oligonucleotides, (iv) to integrate and scale our VeraCode technology,
    (v) to scale further oligo synthesis output and technology to satisfy
    market demand derived from our collaboration with Invitrogen, together
    with other factors detailed in our filings with the Securities and
    Exchange Commission including our recent filings on Forms 10-K and
    10-Q or in information disclosed in public conference calls, the date
    and time of which are released beforehand. We disclaim any intent or
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