Empresas y finanzas

Cytori Reports 2006 Fourth Quarter and Year-End Results; Reviews 2006 Progress and Provides 2007 Outlook



    Cytori Therapeutics (NASDAQ:CYTX) (Frankfurt:XMPA) reports
    financial results for the quarter and year ended December 31, 2006,
    reviews 2006 progress, and provides 2007 outlook.

    "In 2006 we made significant strides toward commercializing the
    Celution(TM) System in early 2008," said Christopher J. Calhoun, chief
    executive officer for Cytori. "This included the first clinical
    experience for the Celution(TM) System as part of a breast
    reconstruction safety and feasibility study, attaining key regulatory
    milestones and adding critical design components to tailor the
    Celution(TM) System to reconstructive surgery.

    "In addition, we laid extensive groundwork to start two
    cardiovascular disease clinical trials. This included the completion
    of important preclinical research that helped us design and implement
    controlled, randomized dose-escalation studies. Our PRECISE chronic
    heart disease trial began enrollment in January 2007 and our APOLLO
    acute heart attack trial is expected to receive approval and begin
    enrolling patients next quarter."

    2007 Outlook

    "Our major 2007 initiatives are to prepare for commercialization,
    execute strategic partnerships and advance our cardiovascular products
    through clinical development," added Mr. Calhoun. "We believe the
    buildup to our 2008 product launch can significantly increase Cytori's
    intrinsic value as we get closer to generating regenerative medicine
    product revenues."

    Cytori anticipates achieving the following milestones in 2007:

    -- Initiate the APOLLO heart attack safety and feasibility trial;

    -- Announce the outcome of the investigator-initiated breast
    reconstruction safety and feasibility study in Japan;

    -- Initiate a multi-center breast reconstruction efficacy trial
    in Europe in patients who underwent partial-mastectomy;

    -- Expand the Celution(TM) System distribution network for
    reconstructive surgery;

    -- Build out internal Celution(TM) System manufacturing
    capabilities to meet anticipated product demand in early 2008;

    -- Pursue commercialization partners for the Celution(TM) System
    in select therapeutic areas; and

    -- Enter a commercialization agreement for adipose stem cell
    banking.

    Financials

    Cash, cash equivalents and short-term investments were $12.9
    million as of December 31, 2006. Subsequent to the end of the year,
    Cytori raised $20 million from an equity offering and entered into an
    agreement to raise $6 million as part of a strategic equity agreement
    with Green Hospital Supply, Inc.

    Total development revenues for the quarter and year ended December
    31, 2006 were $5.2 million and $6.5 million, respectively, compared to
    $235,000 and $371,000, respectively, for the same period in 2005. The
    increase in development revenues in the fourth quarter and full year
    2006 is due to the recognition of deferred revenue related to the
    Olympus-Cytori Joint Venture by achieving certain regulatory,
    preclinical development and Celution(TM) System development
    milestones. Product revenues from our non-core biomaterials products
    for the quarter and year ended December 31, 2006 were $363,000 and
    $1.5 million, respectively, compared to $858,000 and $5.6 million for
    the same periods in 2005.

    Research and development expenses for the quarter and year ended
    December 31, 2006 were $5.2 million and $22.0 million, respectively,
    compared to $4.9 million and $15.5 million, respectively, for the same
    periods in 2005. The increase in R&D for the full year 2006 is
    attributed to additional preclinical studies, preparations for
    upcoming clinical trials, increased Celution(TM) System development
    expenses to attain regulatory approvals, and internal scale-up for
    manufacturing of devices and consumables for clinical trials.

    General and administrative expenses for the quarter and year ended
    December 31, 2006 were $2.5 million and $12.5 million, respectively,
    compared to $2.2 million and $10.2 million, respectively, for the same
    periods in 2005. Net loss for the quarter and year ended December 31,
    2006 was $1.9 million, or $(0.10) per common share, and $25.4 million,
    or $(1.53) per common share. This compares to a net loss of $14.4
    million, or $(0.96) per common share, and $26.5 million, or $(1.80)
    per common share, respectively, for the same periods in 2005.

    Conference Call Information

    The management of Cytori Therapeutics will host a conference call
    today at 10:00 a.m. Eastern Daylight Time (EDT) or 4:00 p.m. Central
    European Summer Time (CEST). The conference call will be webcast live
    and may be accessed under "Events & Webcasts" in the Investor
    Relations section of the Company's website at http://www.cytoritx.com.
    The archived version of the webcast will be available two hours after
    the call on the Company's website and accessible for 14 days. A
    telephone replay will be available for one week. To access the replay,
    please call +1 (303) 590-3000 (PIN: 11086131#).

    Cytori Therapeutics

    Cytori Therapeutics is developing and seeks to commercialize stem
    and regenerative cell therapies for cardiovascular disease,
    reconstructive surgery and many other serious chronic and life
    threatening conditions. To provide these therapies, physicians remove
    a small amount of a patient's fat, also known as adipose tissue, and
    run it through Cytori's Celution(TM) System. This System quickly
    separates and concentrates stem and regenerative cells from adipose
    tissue so they may be quickly administered back to the patient about
    an hour later. This system will dramatically improve the way in which
    personalized cell-based therapies can be delivered to patients.
    www.cytoritx.com

    Cautionary Statement Regarding Forward-Looking Statements

    This press release includes forward-looking statements regarding
    events, trends and prospects of our business, which may affect our
    future operating results and financial position. Such statements are
    subject to risks and uncertainties that could cause our actual results
    and financial position to differ materially. Some of these risks and
    uncertainties include our history of operating losses, the need for
    further financing, regulatory uncertainties, dependence on performance
    of third parties, and other risks and uncertainties described (under
    the heading "Risk Factors") in Cytori Therapeutics' Form 10-K annual
    report for the year ended December 31, 2006. We assume no
    responsibility to update or revise any forward-looking statements to
    reflect events, trends or circumstances after the date they are made.

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    Consolidated Balance Sheets

    As of December 31,
    --------------------------------
    2006 2005
    ---------------- ---------------

    Assets
    Current assets:
    Cash and cash equivalents $ 8,902,000 $ 8,007,000
    Short-term investments, available-
    for-sale 3,976,000 7,838,000
    Accounts receivable, net of
    allowance for doubtful accounts of
    $2,000 and $9,000 in 2006 and
    2005, respectively 225,000 816,000
    Inventories, net 164,000 258,000
    Other current assets 711,000 621,000
    ---------------- ---------------

    Total current assets 13,978,000 17,540,000

    Property and equipment held for sale,
    net 457,000 --
    Property and equipment, net 4,242,000 4,260,000
    Investment in joint venture 76,000 --
    Other assets 428,000 458,000
    Intangibles, net 1,300,000 1,521,000
    Goodwill 4,387,000 4,387,000
    ---------------- ---------------

    Total assets $ 24,868,000 $ 28,166,000
    ================ ===============

    Liabilities and Stockholders' Deficit
    Current liabilities:
    Accounts payable and accrued
    expenses $ 5,587,000 $ 6,129,000
    Current portion of long-term
    obligations 999,000 952,000
    ---------------- ---------------

    Total current liabilities 6,586,000 7,081,000

    Deferred revenues, related party 23,906,000 17,311,000
    Deferred revenues 2,389,000 2,541,000
    Option liabilities 900,000 5,331,000
    Long-term deferred rent 741,000 573,000
    Long-term obligations, less current
    portion 1,159,000 1,558,000
    ---------------- ---------------

    Total liabilities 35,681,000 34,395,000

    Commitments and contingencies
    Stockholders' deficit:
    Preferred stock, $0.001 par value;
    5,000,000 shares authorized; -0-
    shares issued and outstanding in
    2006 and 2005 -- --
    Common stock, $0.001 par value;
    95,000,000 shares authorized;
    21,612,243 and 18,194,283 shares
    issued and 18,739,409 and
    15,321,449 shares outstanding in
    2006 and 2005, respectively 22,000 18,000
    Additional paid-in capital 103,053,000 82,196,000
    Accumulated deficit (103,460,000) (78,013,000)
    Treasury stock, at cost (10,414,000) (10,414,000)
    Accumulated other comprehensive
    income (loss) 1,000 (16,000)
    Amount due from exercises of stock
    options (15,000) --
    ---------------- ---------------

    Total stockholders' deficit (10,813,000) (6,229,000)
    ---------------- ---------------

    Total liabilities and
    stockholders' deficit $ 24,868,000 $ 28,166,000
    ================ ===============
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    Income Statement

    For the Years Ended December 31,
    ----------------------------------------
    2006 2005 2004
    ------------- ------------- ------------

    Product revenues:
    Sales to related party $ 1,451,000 $ 5,634,000 $ 4,085,000
    Sales to third parties -- -- 2,237,000
    ------------- ------------- ------------

    1,451,000 5,634,000 6,322,000

    Cost of product revenues 1,634,000 3,154,000 3,384,000
    ------------- ------------- ------------

    Gross profit (loss) (183,000) 2,480,000 2,938,000
    ------------- ------------- ------------

    Development revenues:
    Development, related party 5,905,000 -- --
    Development 152,000 51,000 158,000
    Research grants and other 419,000 320,000 338,000
    ------------- ------------- ------------

    6,476,000 371,000 496,000
    ------------- ------------- ------------
    Operating expenses:
    Research and development 21,977,000 15,450,000 10,384,000
    Sales and marketing 2,055,000 1,547,000 2,413,000
    General and administrative 12,547,000 10,208,000 6,551,000
    Change in fair value of
    option liabilities (4,431,000) 3,645,000 --
    Restructuring charge -- -- 107,000
    Equipment impairment charge -- -- 42,000
    ------------- ------------- ------------

    Total operating expenses 32,148,000 30,850,000 19,497,000
    ------------- ------------- ------------

    Operating loss (25,855,000) (27,999,000) (16,063,000)
    ------------- ------------- ------------

    Other income (expense):
    Gain on sale of assets -- 5,526,000 --
    Gain on sale of assets,
    related party -- -- 13,883,000
    Interest income 708,000 299,000 252,000
    Interest expense (199,000) (137,000) (177,000)
    Other income (expense), net (27,000) (55,000) 15,000
    Equity loss from investment
    in joint venture (74,000) (4,172,000) --
    ------------- ------------- ------------

    Total other income, net 408,000 1,461,000 13,973,000
    ------------- ------------- ------------

    Net loss (25,447,000) (26,538,000) (2,090,000)
    ------------- ------------- ------------

    Other comprehensive income
    (loss) -- unrealized holding
    income (loss) 17,000 16,000 (58,000)
    ------------- ------------- ------------

    Comprehensive loss $(25,430,000) $(26,522,000) $(2,148,000)
    ============= ============= ============

    Basic and diluted net loss
    per common share $ (1.53) $ (1.80) $ (0.15)
    ============= ============= ============

    Basic and diluted weighted
    average common shares 16,603,550 14,704,281 13,932,390
    ============= ============= ============
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