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Veterinary Laboratories Agency, U.K. and Applied Biosystems to Commercialize New Avian Influenza and Newcastle Disease Detection Kit



    Applied Biosystems (NYSE: ABI), an Applera Corporation business,
    and the Veterinary Laboratories Agency (VLA), a UK government agency
    specializing in animal disease surveillance and veterinary research,
    today announced a strategic collaboration to manufacture and
    commercialize the VLA's molecular avian influenza and Newcastle
    disease environmental detection kits. These kits are expected to be
    broadly available in Europe and other parts of the world, such as Asia
    and Africa. This collaboration is intended to help early detection of
    these harmful bird diseases, which is a critical step in managing the
    threat posed by these diseases.

    The VLA has used these tests to confirm that the avian flu strain
    that recently killed 2,600 turkeys in Suffolk, England was the H5N1
    virus. It was the first reported case of H5N1 on a UK commercial farm.
    The agency said that early detection enabled immediate response to
    contain the outbreak. These tests have also been used in a follow-up
    enhanced survey of the wild bird population.

    The goal of the VLA and Applied Biosystems agreement is to make
    these types of tests - known as assays - more readily available for
    the same type of early warning detection in various countries. In
    addition to the Influenza A virus and its H5 subtype, the assays are
    also expected to address the H7 subtype and Newcastle disease. The new
    assays are designed to rapidly and reliably detect a broad range of
    avian influenza strains in laboratory samples.

    "This collaboration agreement between Veterinary Laboratories
    Agency and Applied Biosystems is an ideal opportunity to combine both
    VLA's experience and expertise of these two very important avian
    diseases and Applied Biosystems' expertise and manufacturing skills,"
    said Professor Steve Edwards, chief executive of VLA. "As with any
    notifiable disease, rapid confirmation is essential for control
    measures to be implemented quickly and to minimise the impact. These
    molecular detection methods should help to improve, sensitivity,
    specificity and turnaround time. We look forward to a long and
    successful partnership."

    Under the terms of the agreement, Applied Biosystems will
    commercialize the VLA real-time PCR assays. Real-time PCR is a
    laboratory method used to simultaneously detect and determine the
    amount of nucleic acids present in samples. Applied Biosystems was
    chosen due to its expertise in the area of avian influenza detection,
    its broad portfolio of avian flu kits based on TaqMan(R) real-time PCR
    technology, its commercial manufacturing scalability and its specialty
    in producing reliable tests that require fewer processing steps.

    The VLA assays are veterinary molecular tests that are used in a
    laboratory. Applied Biosystems intends to further develop these assays
    in a new dry format designed to render more reliable results by
    consolidating steps in the testing process and minimizing manual
    procedures. The VLA will perform the validation prior to the release
    of the tests, which are intended for use in animal health laboratories
    around the world outside the United States.

    Applied Biosystems currently has an installed base of over 1,400
    real-time PCR platforms in public health laboratories across Europe,
    Asia, and Africa capable of running avian influenza TaqMan(R) assays.
    Applied Biosystems' current TaqMan(R) Influenza A/H5 Detection Kits
    are manufactured in Warrington, UK. Today's announcement extends the
    Applied Biosystems international initiative to ensure that detection
    kits and up-to-date genomic data are available for priority infectious
    disease threats.

    "Laboratories responsible for disease surveillance in many
    different countries continue to increase preparations for any possible
    outbreak of avian influenza and other infectious diseases," said Lars
    Holmkvist, president of Applied Biosystems, Europe. "Providing animal
    health laboratories with the tools for a reliable early warning system
    demonstrates Applied Biosystems' commitment to support a global
    network of laboratories and to partner with leading agencies, such as
    the VLA, to bring reliable tests to market as quickly as possible."

    Avian influenza is an infectious disease of birds caused by the
    type A strains of the influenza virus. The H5N1 subtype has evolved
    into a virus that has the potential to infect humans. If contracted,
    it has the capability to cause serious illness or death in extreme
    cases. Certain strains of influenza A virus also have the ability to
    mutate into strains with differing pathogenic profiles. Newcastle
    disease virus is a highly contagious, notifiable disease caused by a
    Paramyxovirus, type 1, that affects domestic poultry and many species
    of wild birds. The clinical signs include depression, lack of
    appetite, respiratory distress, coughing and sneezing.

    For research use only. Not for use in diagnostic procedures.

    Applied Biosystems' influenza detection products are for research
    use only and for health agency epidemiological use only in countries
    outside of the United States. They have not been cleared or approved
    by the United States Food and Drug Administration or any other
    regulatory agency, or under the European IVD Directive, for diagnostic
    or other clinical use, and are not intended and should not be used for
    diagnostic or any other clinical purposes. TaqMan(R) Influenza A/H5
    Detection Kits and Applied Biosystems' other influenza detection kits
    are not for sale in the United States except under special research
    use only certifications.

    About Applera Corporation and Applied Biosystems

    Applera Corporation consists of two operating groups. The Applied
    Biosystems Group serves the life science industry and research
    community by developing and marketing instrument-based systems,
    consumables, software, and services. Customers use these tools to
    analyze nucleic acids (DNA and RNA), small molecules, and proteins to
    make scientific discoveries and develop new pharmaceuticals. Applied
    Biosystems' products also serve the needs of some markets outside of
    life science research, which we refer to as "applied markets," such as
    the fields of: human identity testing (forensic and paternity
    testing); biosecurity, which refers to products needed in response to
    the threat of biological terrorism and other malicious, accidental,
    and natural biological dangers; and quality and safety testing, for
    example in food and the environment. Applied Biosystems is
    headquartered in Foster City, CA, and reported sales of over $1.9
    billion during fiscal 2006. The Celera Group is primarily a molecular
    diagnostics business that is using proprietary genomics and proteomics
    discovery platforms to identify and validate novel diagnostic markers,
    and is developing diagnostic products based on these markers. Celera
    maintains a strategic alliance with Abbott Laboratories for the
    development and commercialization of molecular, or nucleic acid-based,
    diagnostic products, and it is also developing new diagnostic products
    outside of this alliance. Through its genomics and proteomics research
    efforts, Celera is also discovering and validating therapeutic
    targets, and it is seeking to develop therapeutic products based on
    these discovered targets through strategic partnerships. Information
    about Applera Corporation, including reports and other information
    filed by the company with the Securities and Exchange Commission, is
    available at http://www.applera.com/, or by telephoning 800.762.6923.
    Information about Applied Biosystems is available at
    http://www.appliedbiosystems.com/.

    About the Veterinary Laboratories Agency:

    VLA is a UK Government, Executive Agency of the Department of
    Environment, Food and Rural Affairs (Defra) and is a regional network
    of 16 laboratories including one in Scotland, two in Wales, a central
    research and diagnostic testing facility near Weybridge in Surrey. The
    Agency is one of the largest research establishments of its kind in
    the world and is internationally recognised as a centre of scientific
    excellence. It has close international links with research institutes,
    universities and commercial companies and acts as an International
    Reference Laboratory for a wide range of infectious and non-infectious
    diseases in farm animals including avian influenza and Newcastle
    disease. The main aim of the Agency is to safeguard public and animal
    health by providing all sectors of the animal health industry with a
    wide range of applied veterinary research and consultancy on diseases
    of farmed livestock, diagnosis of diseases of statutory and public
    health importance and surveillance of new and emerging diseases
    throughout the country. These services are delivered through a series
    of integrated science programmes which include research and
    surveillance into TSEs, tuberculosis, avian influenza, food and
    environmental safety, the identification of new and emerging
    veterinary diseases and a comprehensive laboratory testing service.

    Applied Biosystems Forward Looking Statements

    Certain statements in this press release are forward-looking.
    These may be identified by the use of forward-looking words or phrases
    such as "should," "expect," and "planned," among others. These
    forward-looking statements are based on Applera Corporation's current
    expectations. The Private Securities Litigation Reform Act of 1995
    provides a "safe harbor" for such forward-looking statements. In order
    to comply with the terms of the safe harbor, Applera Corporation notes
    that a variety of factors could cause actual results and experience to
    differ materially from the anticipated results or other expectations
    expressed in such forward-looking statements. These factors include
    but are not limited to: (1) rapidly changing technology and dependence
    on the development and customer acceptance of new products; (2) risk
    whether the new kits will be successfully manufactured and
    commercialized through the collaboration, (3) sales dependent on
    customers' capital spending policies; and (4) other factors that might
    be described from time to time in Applera Corporation's filings with
    the Securities and Exchange Commission. All information in this press
    release is as of the date of the release, and Applera does not
    undertake any duty to update this information, including any
    forward-looking statements, unless required by law.

    Copyright(C) 2007. Applera Corporation. All rights reserved.

    Applied Biosystems, AB (Design), Applera and Celera are registered
    trademarks of Applera Corporation or its subsidiaries in the US and/or
    certain other countries. TaqMan is a registered trademark of Roche
    Molecular Systems, Inc.