Scottish Medicines Consortium Issues Positive Advice on Evoltra(R)



    Bioenvision Limited (NasdaqGM: BIVN) today announced the Scottish
    Medicines Consortium (SMC) released positive advice on the use of
    Evoltra(R) (clofarabine) within NHS Scotland.

    The release of this positive advice ensures funding is now
    available for Evoltra, which is a new treatment option for children
    with acute lymphoblastic leukaemia (ALL) who have relapsed or are
    refractory to the standard treatment options.

    "The prognosis for children with relapsed/refractory ALL is very
    poor, and the availability of Evoltra is great news for patients and
    their families," said Hugh Griffith, Chief Operating Officer of
    Edinburgh based Bioenvision. "We believe that Evoltra offers genuine
    hope and a real chance for prolonged survival in children who have
    exhausted all standard therapies and are very pleased that the SMC has
    issued this positive advice and that the funding for Evoltra will now
    be in place."

    "Treatment for children with leukaemia in Scotland has improved
    dramatically over the last three decades. However, for children with
    resistant disease the prognosis remains poor and any new drug or
    treatment that offers hope for this group of patients and their
    families is welcomed," commented Dr Brenda Gibson, Consultant
    Haematologist, Royal Hospital for Sick Children, Yorkhill, Glasgow,
    Scotland, UK.

    About Evoltra(R) (clofarabine)

    The European Marketing Authorization for Evoltra(R) (clofarabine)
    is for "the treatment of acute lymphoblastic leukaemia (ALL) in
    paediatric patients who have relapsed or are refractory to at least
    two prior regimens and where there is no other treatment option
    anticipated to result in a durable response. Safety and efficacy have
    been assessed in studies of patients