Empresas y finanzas

Biogen Idec to Acquire Fumapharm AG; Consolidates Ownership of Oral Compound BG-12 Being Studied for Multiple Sclerosis



    Biogen Idec (NASDAQ: BIIB) and Fumapharm AG, a privately
    held pharmaceutical company, today announced that they have signed a
    definitive agreement for the acquisition of Fumapharm by Biogen Idec.
    Fumapharm AG, founded in Switzerland in 1983, develops
    therapeutics derived from fumaric acid esters for patients with high
    unmet medical need. The company has two products: FUMADERM(R), a
    commercial product available in Germany for the treatment of
    psoriasis, and BG-12, a clinical-stage product that has been jointly
    developed with Biogen Idec. BG-12, an oral fumarate, is being studied
    for the treatment of multiple sclerosis (MS) and psoriasis.
    "This acquisition supports our goal of developing innovative
    therapeutic options for people living with MS," said James C. Mullen,
    Biogen Idec's President and Chief Executive Officer. "We look forward
    to continuing the development of BG-12, a promising oral compound in
    MS, as well as expanding our European operations by working with
    Fumapharm's existing partners to provide FUMADERM to psoriasis
    patients in Germany."
    On May 30, 2006, Biogen Idec and Fumapharm announced positive
    results from a Phase II study designed to evaluate the efficacy and
    safety of BG-12 in patients with relapsing-remitting MS. The study
    achieved its primary endpoint, demonstrating that treatment with BG-12
    led to a statistically significant reduction in the total number of
    gadolinium-enhancing brain lesions as measured by MRI with six months
    of treatment versus placebo.
    "Biogen Idec is perfectly positioned to continue the development
    of BG-12 because of its global commercial and regulatory experience
    and unsurpassed expertise in MS. We are proud of the work that
    Fumapharm has accomplished in the last 20 years and are confident that
    Biogen Idec will continue our legacy of helping patients," said Dr.
    Hans Peter Strebel, Chairman and CEO of Fumapharm.
    The transaction, which has been approved by the boards of
    directors of both companies and is subject to customary closing
    conditions, is expected to close within the next two months. Upon
    completion, Biogen Idec will acquire all of the issued and outstanding
    shares of the capital stock of Fumapharm and will take over
    manufacture and sale of FUMADERM for the treatment of psoriasis in
    Germany through Fumapharm's existing network. Financial terms of the
    transaction were not disclosed.

    About BG-12

    In October 2003, Biogen Idec licensed certain exclusive worldwide
    rights to develop and market BG-12, oral fumarate derivative with an
    immunomodulatory mechanism of action, from Fumapharm. Biogen Idec and
    Fumapharm are evaluating BG-12 in a range of diseases, including MS
    and psoriasis. In April 2005, the companies announced that the primary
    endpoint was met in a Phase III study designed to evaluate the
    efficacy and safety of BG-12 in the treatment of moderate to severe
    psoriasis.
    In the Phase II MS study, the most commonly reported adverse
    events were flushing, gastrointestinal disorders, headache, and
    nasopharyngitis. Liver enzyme elevations were reported in 2% to 8% of
    the active treatment groups, compared to 5% in the placebo group.
    Infection rates were balanced.

    About Fumapharm AG and FUMADERM

    Fumapharm is a privately held pharmaceutical company headquartered
    in Lucerne, Switzerland. For more information, please visit
    http://www.fumapharm.ch.
    FUMADERM, an oral product containing fumaric acid esters, was
    approved in Germany in 1994 where it is the leading prescription for
    oral systemic treatment of severe psoriasis. Fumedica GmbH distributes
    FUMADERM in Germany.

    About Biogen Idec

    Biogen Idec creates new standards of care in oncology, neurology
    and immunology. As a global leader in the development, manufacturing,
    and commercialization of novel therapies, Biogen Idec transforms
    scientific discoveries into advances in human healthcare. For product
    labeling, press releases and additional information about the company,
    please visit www.biogenidec.com.

    Biogen Idec Safe Harbor

    This press release contains forward-looking statements regarding
    the acquisition of Fumapharm, the development of BG-12, and the
    availability of FUMADERM. These statements are based on the companies'
    current beliefs and expectations. Drug development involves a high
    degree of risk. Factors which could cause actual results to differ
    materially from the companies' current expectations include the risk
    that unexpected concerns may arise from additional data or analysis;
    that regulatory authorities may require additional information,
    further studies, or may fail to approve the drug; the impact of
    competitive products on the company's products, a change in market
    acceptance of FUMADERM; and that the company may encounter other
    unexpected hurdles. For more detailed information on the risks and
    uncertainties associated with Biogen Idec's drug development and other
    activities, see the section entitled "Risk Factors" in Biogen Idec's
    annual report on form 10-K for the fiscal year ended December 31, 2005
    that was filed with the Securities and Exchange Commission, as well as
    the other periodic and current reports of Biogen Idec filed with the
    Securities and Exchange Commission. Biogen Idec assumes no obligation
    to update any forward-looking statements, whether as a result of new
    information, future events or otherwise.