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BIOBASE's ExPlain(TM) Analysis System and TRANSFAC(R) Database Achieve GeneChip-compatible(TM) Status with Affymetrix GeneChip(R) Microarray Platform



    BIOBASE announced today that it has joined the Affymetrix
    GeneChip-compatible Applications Program, and its ExPlain(TM) Analysis
    System and TRANSFAC(R) database has achieved GeneChip-compatible(TM)
    status with the Affymetrix Inc. (Nasdaq: AFFX) GeneChip(R) microarray
    platform. As a GeneChip-compatible software provider, BIOBASE is
    committed to seamlessly integrating its applications with the
    Affymetrix GeneChip platform.

    BIOBASE's award winning ExPlain(TM) Analysis System provides a
    novel, fully integrated analysis pipeline for explaining biology on
    the levels of transcription regulation and pathway analysis. In
    addition, TRANSFAC(R) provides data on transcription factors, their
    experimentally-proven binding sites, and regulated genes. Both
    products offer the ability to analyze high throughput experimental
    data such as Affymetrix microarrays for the identification of future
    research targets.

    According to Holger Karas, Senior Vice President of Business
    Development, "Combining the vast repository of information available
    in our products with Affymetrix and the GeneChip-compatible
    Applications Program offers our customers an unparalleled opportunity
    to advance their current research and quickly develop experimental
    direction for future study."

    "Affymetrix is pleased to welcome BIOBASE to the family of
    GeneChip-compatible software providers," said Steve Lincoln, vice
    president of Informatics at Affymetrix. "The coupling of the rich
    content of TRANSFAC with the analytical methods in ExPlain can result
    in a greater understanding of disease states and their associated
    biological processes to users of GeneChip microarrays."

    About BIOBASE GmbH

    BIOBASE (www.biobase-international.com), based in Wolfenbuttel
    (Germany), with branch offices in Beverly, MA (USA) and Bangalore
    (India) is the leading provider of expertly-curated biological
    databases and sophisticated software tools. The BIOBASE Knowledge
    Library includes but is not limited to the TRANSFAC(R), TRANSPATH(R),
    YPD(TM)and HumanPSD(TM) databases. In combination, the systems biology
    analysis platform ExPlain(TM) offers the identification of molecular
    networks and key molecules critical to discovery research. BIOBASE
    also provides a growing portfolio of databases of third parties such
    as BRENDA(R) and HGMD(R). Our customers include the leading academic
    and research institutions around the world. For more information,
    please visit our website at www.biobase-international.com.

    ABOUT THE AFFYMETRIX DEVELOPERS' NETWORK (ADN)

    Through one of the largest third-party software developer
    communities within the life science industry, Affymetrix works with
    its software developers to provide a broad spectrum of solutions for
    leveraging gene expression and genetic variation analysis in both
    biomedical research and development. Membership in ADN is free of
    charge for both commercial and academic software developers. For more
    information please visit www.affymetrix.com/genechip/developer. View
    the GeneChip-compatible Software Solutions Catalog at
    www.affymetrix.com/genechip/compatible.

    About Affymetrix

    Affymetrix GeneChip(R) microarray technology is the
    industry-standard tool for analyzing complex genetic information.
    After inventing microarray technology in the late 1980s, Affymetrix
    scientists have been dedicated to developing innovative products that
    provide researchers with a more complete view of the genome. These
    products continue to accelerate genetic research and enable scientists
    to develop diagnostics and tailor treatments for individual patients
    by identifying and measuring the genetic information associated with
    complex diseases.

    Today, Affymetrix technology is used by the world's top
    pharmaceutical, diagnostic and biotechnology companies, as well as
    leading academic, government and not-for-profit research institutes.
    More than 1,500 systems have been shipped around the world and more
    than 8,500 peer-reviewed papers have been published using the
    technology.

    Affymetrix is headquartered in Santa Clara, Calif., and has
    manufacturing facilities in Sacramento, Calif., and Singapore. The
    company has about 1,100 employees worldwide and maintains sales and
    distribution operations across Europe and Asia. For more information
    about Affymetrix, please visit the company's website at
    www.affymetrix.com.