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Amgen Announces International Nephrology Research Initiative with Fresenius Medical Care



    Amgen and Fresenius to Evaluate Optimization of Care for Patients with Chronic Kidney Disease

    Amgen (Europe) GmbH today announced an international research
    initiative with Fresenius Medical Care that will help optimize care
    for patients with chronic kidney disease (CKD). The multi-year
    agreement seeks to improve the quality of medical care for patients
    suffering from CKD related to the treatment of anaemia, secondary
    hyperparathyroidism (SHPT) and other associated illnesses, through
    data analyses, education and research.

    "Amgen and Fresenius Medical Care are well known for their
    commitment to developing and establishing new therapies for the
    benefit of patients with end-stage renal disease worldwide," said
    Daniele Marcelli, M.D., Fresenius Medical Care. "We selected Amgen
    based on their clinical expertise and leadership and innovation in
    nephrology, which has led to significant clinical outcome improvements
    in dialysis patients, and look forward to working with Amgen on this
    important initiative."

    "This agreement with Fresenius Medical Care demonstrates our
    mutual commitment to improving the standard of care for patients
    suffering from CKD," said Bill Sheridan, M.D., vice president, Amgen
    International Medical Affairs. "By combining Fresenius Medical Care's
    demonstrated expertise in providing state of the art care for CKD and
    dialysis patients with Amgen's two decades of innovative nephrology
    therapeutics, we hope to further improve patients' lives."

    About Amgen

    Amgen discovers, develops and delivers innovative human
    therapeutics. A biotechnology pioneer since 1980, Amgen was one of the
    first companies to realize the new science's promise by bringing safe
    and effective medicines from lab, to manufacturing plant, to patient.
    Amgen therapeutics have changed the practice of medicine, helping
    millions of people around the world in the fight against cancer,
    kidney disease, rheumatoid arthritis, and other serious illnesses.
    With a deep and broad pipeline of potential new medicines, Amgen
    remains committed to advancing science to dramatically improve
    people's lives. To learn more about our pioneering science and our
    vital medicines, visit www.amgen.com.

    About Fresenius Medical Care

    Fresenius Medical Care is the world's largest integrated provider
    of products and services for individuals undergoing dialysis because
    of chronic kidney failure, a condition that affects more than
    1,400,000 individuals worldwide. Through its network of 2,085 dialysis
    clinics in North America, Europe, Latin America, Asia-Pacific and
    Africa, Fresenius Medical Care provides dialysis treatment to 161,433
    patients around the globe. Fresenius Medical Care is also the world's
    leading provider of dialysis products such as hemodialysis machines,
    dialyzers and related disposable products. Fresenius Medical Care is
    listed on the Frankfurt Stock Exchange (FME, FME3) and the New York
    Stock Exchange (FMS, FMS-p). For more information about Fresenius
    Medical Care visit the Company's website at www.fmc-ag.com.

    Amgen Forward-Looking Statement

    This news release contains forward-looking statements that involve
    significant risks and uncertainties, including those discussed below
    and others that can be found in our Form 10-K for the year ended Dec.
    31, 2005 and in our periodic reports on Form 10-Q and Form 8-K. Amgen
    is providing this information as of the date of this news release and
    does not undertake any obligation to update any forward-looking
    statements contained in this document as a result of new information,
    future events or otherwise.

    No forward-looking statement can be guaranteed and actual results
    may differ materially from those we project. The Company's results may
    be affected by our ability to successfully market both new and
    existing products domestically and internationally, sales growth of
    recently launched products, difficulties or delays in manufacturing
    our products and regulatory developments (domestic or foreign)
    involving current and future products and manufacturing facilities. In
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    cost containment as well as possible U.S. legislation affecting
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    could identify side effects or manufacturing problems with our
    products after they are on the market. In addition, we compete with
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    as for the discovery and development of new products. Discovery or
    identification of new product candidates cannot be guaranteed and
    movement from concept to product is uncertain; consequently, there can
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