Kyowa Hakko Kirin Group: Medium-Term Business Plan FY2008-2010



    Kyowa Hakko Kogyo Co., Ltd. (Kyowa Hakko)(TOKYO:4151) today announced

    the Kyowa Hakko Kirin Group Medium-term Business Plan for the period

    from fiscal 2008-2010.
    The core of the plan is based on the integration of Kyowa Hakko and

    Kirin Pharma Company, Limited (Kirin Pharma) that was announced on

    October 22, 2007. In accordance with the strategic alliance between

    Kyowa Hakko Group and Kirin Group, the plan formulates the strategic

    direction and financial targets for the newly created Kyowa Hakko Kirin

    Group and the specific steps that will be taken to achieve our goals

    over the next three years.
    Yuzuru Matsuda, President and CEO of Kyowa Hakko said "ËœThe

    integration of our business with Kirin Pharma to form Kyowa Hakko Kirin

    is proceeding smoothly and on schedule. We clearly exceeded the targets

    of our previous medium-term business plan and our new plan aims to

    establish Kyowa Hakko Kirin Group as a world-class, R&D-focused life

    sciences company, based on biotechnology and with the pharmaceuticals

    business at its core.´
    1. Basic Group Policies
    Kyowa Hakko Kirin Group has established the following basic Group

    policies for the period of the medium-term plan:
    (1) To rapidly integrate the personnel and the distinct corporate

    cultures of the two companies in order to realize our vision and achieve

    Group synergies.
    (2) To actively commit business resources to our two core businesses

    Pharmaceuticals and Bio-Chemicals, and further strengthen profitability

    in pursuit of growth. We also aim to build Chemicals and Food businesses

    that are resilient to economic fluctuations and can record stable

    income, while contributing to the stability of Group profits.
    (3) To ensure thorough compliance, and by providing high quality

    products, aim to be a Group that is trusted for its security and safety.
    (4) To strengthen our competitiveness through the relentless pursuit of

    corporate reform, while aiming to strengthen our business and improve

    the efficiency of research and development through alliances, and merger

    and acquisition.
    (5) To pursue synergies with companies in similar business within the

    Kirin Group.
    (6) To generate a sustained flow of groundbreaking new pharmaceuticals

    by developing the Pharmaceuticals business of Kyowa Hakko Kirin Group

    with strength in R&D as our growth driver.

    = = = = = = = = = = =

    2. Targets

    - - - - - -

    - - - - - -

    (1) Numerical targets for fiscal year 2010 (consolidated)

    - - - - - -

    Net sales

    JPY 513 billion

    - - - - - -

    Operating income (before goodwill amortization)

    JPY 73.0 billion

    - - - - - -

    Operating income (after goodwill amortization)

    JPY 63.3 billion

    - - - - - -

    ROIC (before goodwill amortization)

    +16%
    - - - - - -

    ROIC (after goodwill amortization)

    +10%
    - - - - - -

    Dividend payout ratio (Based on profit before goodwill amortization)

    +30%
    - - - - - -

    Note: The integration is a reverse acquisition under the rules for

    accounting for business combinations and following integration, in

    the consolidated financial statements of Kyowa Hakko Kirin Group

    Kyowa Hakko is treated as having been acquired by Kirin Pharma

    under the Purchase Method and goodwill is recorded. At the current

    time goodwill arising from the reverse acquisition is expected to

    be approximately JPY 190.0 billion and based on an expected

    amortization period of 20 years a provisional calculation of

    goodwill amortization expenses has been made.

    - - - - - -

    = = = = = = = = = = =

    (2) Segmental targets for fiscal 2010 (consolidated)

    - - - - - -

    (JPY billion)

    - - - - - -

    Pharmaceuticals

    Bio-Chemicals

    Chemicals

    Food
    - - - - - -

    Net Sales

    225.0

    98.0

    117.0

    45.0
    - - - - - -

    Operating income (Before goodwill amortization)

    52.5

    11.0

    6.0

    2.5
    - - - - - -

    Operating income (After goodwill amortization)

    43.8

    10.4

    5.9

    2.2
    - - - - - -

    ROIC (Before goodwill amortization)

    +23%

    +11%

    +9%

    +7%
    - - - - - -

    3. Main strategies for the Plan period
    (1) Pharmaceuticals
    1. Research and Development
    -- Aim to generate innovative candidate products for development.
    Target: Each year, two antibody compounds and two low-molecular-weight

    compounds to enter development.
    -- Pursue a synthesis of the KM Mouse, HSKI, Potelligent and Complegent

    technologies
    -- Create a research framework that fully realizes the strengths of each

    company.

    Development Research Laboratories (Maebashi) and certain functions of

    the Discovery Research Laboratories (Takasaki) to be transferred to

    Fuji Research Park

    Certain functions of the Discovery Research Laboratories (Takasaki)

    and Frontier Laboratories to be transferred to Tokyo Research Park

    Integrate bio-pharmaceuticals production technology development and

    clinical pharmaceutical production functions at the Bio-CMC R&D

    Laboratories (Takasaki)

    -- Establish an optimal international development framework.
    -- Pursue the creation of unique technology.
    2. Production
    -- Establish top class bio-pharmaceutical production technology.
    -- Consolidate antibody production facilities to create an efficient

    production framework.
    3. Domestic sales
    -- Focus resource allocation in the Renal area and aim to win the

    leading market share in the ESA* market. (* Erythropoiesis Stimulating

    Agent)
    -- Further enhance our presence in the Cancer area.
    -- Expand our share in the Allergy area.
    -- Aim to enhance our presence by strengthening relationships with

    specialist distributors.
    4. Overseas business
    -- Aim to maximize the value of the antibodies business.
    -- Establish the foundations for long-term profits in Asia
    -- Consider developing an in-house sales capability in Europe and the

    U.S.
    (2) Bio-Chemicals
    1. Expand sales of amino acids
    -- Expand sales in growth areas of the amino acid market such as

    infusions and medical foods, while upgrading and strengthening amino

    acid production facilities.
    2. Strengthen links with Daiichi Fine Chemical
    -- Aim to create high value-added fine chemical products by combining

    fermentation technology and synthesis technology.
    3. Develop the domestic healthcare business
    -- Expand business by focusing on increasing the market penetration of

    functional fermented materials such as new healthcare material

    citrulline and core product ornithine.
    *Plan to establish Kyowa Hakko Bio Co., Ltd. as a separate company on

    October 1, 2008.
    (3) Chemicals
    1. Strengthen business foundations
    -- Achieve stable profits from existing core products, mainly basic

    chemicals.
    -- Further expand sales of environment-friendly specialty chemicals.
    2. Create distinctive products and businesses
    -- Actively consider commercialization in the oxo-related product domain.
    -- Aim to create new products with a focus on raw materials for

    lubricant oils, recording materials and waterborne resins.
    (4) Food
    1. Seasonings
    -- Maintain a leading share in natural seasonings and fermented

    seasonings for processed food manufacturers.
    -- Aim to increase share in the growing market for prepared foods and

    develop business in the Chinese market.
    2. Bread ingredients
    -- Maintain our leading position as solutions-type manufacturer of

    specialty bread ingredient products such as flavorings and improvers.
    4. Strengthen Group Businesses
    In accordance with the core aim of our strategic alliance, consider and

    promote integration and alliances between non-pharmaceutical businesses

    of the two Groups.
    (1) In the Food business we plan to integrate Kyowa Hakko Foods

    Specialties and Kirin Food-Tech and establish the integrated business as

    an important contributor to the Kirin Group´s

    long-term vision of realizing a quantum leap in growth in the area of

    food & health.
    April 1, 2009: Establish Kirin Kyowa Foods Company, Limited
    January 1, 2011: The merged company to become a wholly-owned subsidiary

    of Kirin Holdings
    (2) Functional and health foods business, Alcohol and other businesses
    We are currently considering functional cooperation with Kirin Yakult

    NextStage Co., Ltd. and Mercian Corporation.
    5. Shareholders´ returns

    We are targeting a dividend payout ratio of 30% or more on the basis

    of consolidated profits prior to the amortization of goodwill.

    Note: In the consolidated financial statements for fiscal 2007 released

    today we are forecasting an annual dividend of JPY 20 per share for the

    fiscal year ending March 2009.
    *The above forecasts are based on information available and

    assumptions made at the time of release of this document about a number

    of uncertain factors that can affect results in the future. It is

    possible that actual results are materially different for a wide variety

    of reasons.
    For further information please access: http://ir.kyowa.co.jp/english/index.cfm

    This document is an English translation of parts of the

    Japanese-language original. All financial information has been prepared

    in accordance with generally accepted accounting principles in Japan. It

    contains forward-looking statements based on a number of assumptions and

    beliefs made by management in light of information currently available.

    Actual financial results may differ materially depending on a number of

    factors, including fluctuations in exchange rates, changing economic

    conditions, legislative and regulatory developments, delays in new

    product launches, and pricing and product initiatives of competitors.